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Meet the CLSI guidelines for urine, GP-16A2, recommend the use of a primary collection *container that holds at least 50 mL, has a wide base and an opening of at least 4 cm *containers that are made of break-resistant plastic *should have a secure lid and be leak-resistent /leak-proof CLSI guidelines GP-16A2, Volume 21, No. 19, Urinalysis and Collection, Transportation, and Preservation of Urine Specimens; Approved Guideline-Second Edition, p. 4-21.